PROGRAM

19th of May, Thursday - Arrival

20th of May, Friday

9:20 - 9:55

Opening remarks (Péter Vilmos) and historical lecture:

"To see what everyone else has seen, and to think what nobody has thought."

Beáta Bugyi, University of Pécs, Hungary


Chair: Brian C. Freeman

9:55 - 10:20

Nanoscopic analysis of actin assembly in developing myofibrils

Szilárd Szikora, BRC Szeged, Hungary


10:20 - 10:45 

Coordination of actin dynamics by formin proteins

Beáta Bugyi, University of Pécs, Hungary


10:45 - 11:10

Formin-mediated nuclear actin assembly: from chromatin dynamics to transcriptional regulation

Robert Grosse, University of Freiburg, Germany


11:10 - 11:30 Coffee break


11:30 - 11:55

MRTF/SRF "inhibitors"

Maria Vartiainen, University of Helsinki, Helsinki, Finland


11:55 - 12:20

Parallel import mechanisms ensure the robust nuclear localization of actin in Drosophila

Péter Vilmos, BRC Szeged, Hungary


12:20 - 12:45

Organisation of transcription by nuclear myosin and actin

Christopher Toseland, University of Sheffield, UK


12:45- 14:00 Lunch


Chair: Piergiorgio Percipalle

14:00 - 14:25

Role of unconventional myosin VI in nucleolar organization and function (zoom lecture)

Maria Jolanta Rędowicz, Nencki Institute of Exp. Biology, Warsaw Poland


14:25 - 14:50

Uncovering the roles of nuclear actin during Drosophila oogenesis (zoom lecture)

Tina Tootle, University of Iowa, Iowa city, USA


14:50 - 15:15

Architectural control of mesenchymal stem cell phenotype through nuclear actin (zoom lecture)

Janet Rubin, University of North Carolina, USA


15:15 - 15:40

DNA repair and mis-repair in 3D (zoom lecture)

Jean Gautier, Columbia University, New York, USA


15:40 - 16:00 Coffee break

17:00 - 18:00 Ship tour on the Tisza river

19:00 - 19:45 City tour by train

20:00 - Dinner in a local restaurant htps://www.facebook.com/napfenymuterem


21st of May, Saturday

Chair: Maria Vartiainen

9:20 - 9:45 

Nuclear actin promotes transcription factory formation through co-phase separation (zoom lecture)

Yujie Sun, Peking University, Peking, China

9:45 - 10:10 

Nuclear F-actin for embryonic development and nuclear reprogramming

Kei Miyamoto, Kindai University, Osaka, Japan


10:10 - 10:35 

The role of actin in the 3D spatial organization of the mammalian genome and impact on gene expression regulation

Piergiorgio Percipalle , New York Univ., Abu Dhabi, United Arab Emirates


10:35 - 11:00

The role of the nucleoskeleton in genome reorganization

Brian C. Freeman, Univ. of Illinois, Urbana, USA


11:00 - 11:20 Coffee Break


11:20 - 11:45 

A mechanoresponsive signalling pathway at the nuclear envelope that promotes nuclear F-actin

Eric O'Neill, University of Oxford, UK


11:45 - 12:10

Mechanical induction of nuclear reprogramming and cellular rejuvenation

G.V. Shivashankar, ETH-Zürich & Paul Scherrer Institute, Switzerland


12:10 - 12:35

Emerging roles of nuclear phosphoinositides in gene expression

Pavel Hozák, Inst. of Mol. Gen. of the ASCR, Prague, Czech Republic


12:35 - 13:00

Concluding remarks/Round table on the future of the network


13:00 - 14:00 Lunch

15:00 - 18:00 Bridge fair + wine festival

18:00 - 21:00 Dinner in a local restaurant https://www.kiskorossyhalaszcsarda.hu/


22nd of May, Sunday - Departure


PARTICIPANTS


  1. BEÁTA BUGYI University of Pécs, Hungary beata.bugyi@aok.pte.hu
  2. BRIAN C. FREEMAN Univ. of Illinois, Urbana, USA bfreeman@life.illinois.edu
  3. JEAN GAUTIER Columbia University, New York, USA jg130@cumc.columbia.edu
  4. ROBERT GROSSE University of Freiburg, Germany robert.grosse@pharmakol.uni-freiburg.de
  5. PAVEL HOZÁK Inst. of Mol. Gen. of the ASCR, Prague, Czech Republic pavel.hozak@img.cas.cz
  6. KEI MIYAMOTO Kindai University, Osaka, Japan kmiyamo@waka.kindai.ac.jp
  7. ERIC O'NEILL University of Oxford, UK eric.oneill@oncology.ox.ac.uk
  8. PIERGIORGIO PERCIPALLE New York Univ., Abu Dhabi, United Arab Emirates pp69@nyu.edu
  9. MARIA JOLANTA RĘDOWICZ Nencki Institute of Exp. Biology, Warsaw Poland j.redowicz@nencki.gov.pl
  10. JANET RUBIN University of North Carolina, USA jrubin@med.unc.edu
  11. GV SHIVASHANKAR ETH-Zürich & Paul Scherrer Institute, Switzerland shiva.gvs@gmail.com
  12. YUJIE SUN Peking University, Peking, China sun_yujie@pku.edu.cn
  13. SZILÁRD SZIKORA BRC Szeged, Hungary szikora.szilard@brc.hu
  14. TINA TOOTLE University of Iowa, Iowa city, USA tina-tootle@uiowa.edu
  15. CHRISTOPHER TOSELAND University of Sheffield, UK c.toseland@sheffield.ac.uk
  16. MARIA VARTIAINEN University of Helsinki, Helsinki, Finland maria.vartiainen@helsinki.fi
  17. PETER VILMOS BRC Szeged, Hungary vilmosp@brc.hu

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